LEARNING OUTCOMES
The students after the end of the course will be able to:
1. Recognize the histopathological lesions and morbid conditions that lead to the development of cancer cells
2. look into his knowledge about histopathology, symptomatology, and prevention of the most common malignant neoplasms
The scope of the course is to enable the students to:
1) recognize and understand the histopathological lesions of the various morbid conditionswhich are the ground for the development of malignant neoplasms, and tumors ingeneral.
2) understand the mechanisms of the development of the main malignant neoplasms, to recognize the risk factors of their development, evaluate their effects upon the humanhealth, and to prevent any fatal outcome of some of them.
3) understand the importance of recent bibliographic data on the most common malignant neoplasms in Greece, Europe and internationally.
The aim of the course is to deepen students’ knowledge on the most basic histopathological lesions that lead to the malignant transformation and the development of cancer, whereas particular reference is made to the most common types and locations of them.
SYLLABUS
Theory
1. Pathological lesions of the cells and tissues. Necrosis, degeneration, hyperplasia, hypertrophy, atrophy, metaplasia.
2. Apoptosis. Apoptosis indicators. Precancerous conditions.
3. Characteristics of neoplastic cell. Ways of metastasis of neoplastic cell. Tumor markers; predictive and preventive markers.
4. Cancer larynx-lung. Risk factors, precancerous conditions, tumor markers, histological types, symptoms, stages, prognosis.
5. Cancer of the stomach, pancreas, liver, colon. Risk factors, precancerous conditions, tumor markers, histological types, symptoms, stages, prognosis.
6. Kidney-bladder. Risk factors, precancerous conditions, tumor markers, histological types, symptoms, stages, prognosis.
7. Adenomatous prostatic hyperplasia. Prostatic-testicular cancer. Risk factors, precancerous conditions, tumor markers, histological types, symptoms, stages, prognosis.
8. Cervicitis. Warts. Cervical cancer. Risk factors, precancerous conditions, tumor markers, histological types, symptoms, stages, prognosis.
9. Adenomatous endometrial hyperplasia-histological types. Corpus uterine cancer. Risk factors, precancerous conditions, tumor markers, histological types, symptoms, stages, prognosis.
10. Fibroadenoma. Papilloma. Fibrocystic disease. Breast-ovarian cancer. Risk factors, precancerous conditions, tumor markers, histological types, symptoms, stages, prognosis.
11. Thyroiditis. Autoimmune thyroiditis-Hashimoto’s thyroiditis. Thyroid gland cancer. Risk factors, precancerous conditions, tumor markers, histological types, symptoms, stages, prognosis.
12. Fibrosclerotic basal cell carcinoma (morphea-like). Melanoma. Risk factors, precancerous conditions, tumor markers, histological types, symptoms, stages, prognosis.
13. Sarcomas-histological types. Giant cell tumor of bones. Osteosarcoma